Study finds Adult Stem Cell Therapy effective alternative to total hip replacement

A new study has revealed that adult stem cell therapy is effective as an alternative to total hip replacement surgery in severe hip osteoarthritis. Adult stem cell therapy, a subcategory of regenerative medicine, revitalizes and regenerates the body’s organs and systems. Regenerative medicine experts say it also reverses and repairs many pending subclinical medical problems […]

A new study has revealed that adult stem cell therapy is effective as an alternative to total hip replacement surgery in severe hip osteoarthritis.

Adult stem cell therapy, a subcategory of regenerative medicine, revitalizes and regenerates the body’s organs and systems. Regenerative medicine experts say it also reverses and repairs many pending subclinical medical problems before they become apparent, including diseases that are age-related, which conventional treatments cannot do.

The study, published in this month’s edition of the Journal of International Case Reports (ICARE), was led by Dr David Ikudaiyisi, Medical Director of Glory Wellness and Regenerative Centre in the USA, Lagos and Abuja.

It was aimed at evaluating the importance of adult stem cell therapy as an alternative to total hip arthroplasty in severe hip osteoarthritis.

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Hip osteoarthritis is one of the leading causes of chronic hip joint pain and disability worldwide. According to the arthritis research and therapy, the global incidence of hip osteoarthritis from 1990 to 2019 increased from 0.74 million to 1.58 million.

The disease causes gradual loss of range of motion and is most often symptomatic during weight-bearing activities. Pain may be felt in the inguinal area or greater trochanter or referred to the thigh and knee, and it is usually accompanied by stiffness of the affected joint.

It is one of the leading causes of chronic hip joint pain and disability worldwide affecting older age individuals: usually symptomatic in the 40s and 50s and is nearly universal by age 80.

Hip replacement surgery, or hip arthroplasty, is a surgical procedure in which an orthopaedic surgeon removes the diseased parts of the hip joint and replaces them with new, artificial parts.

The study followed up a patient for 24 months. The case report started on th 13/11/2020.

“Diagnosed with severe bilateral hip osteoarthritis. The patient had a left total hip arthroplasty for left severe hip osteoarthritis one and a half years prior to presentation and wished to have a procedure with adult stem cell therapy on the right hip as she did not want another surgical procedure done.

“The patient provided written informed consent to undergo the experimental clinical procedure as well as consent to publication of outcomes, images, and data.

“The treatment was done in three sessions. The first session was a combination of MSCs {ADSCs (svf) and BMAC} plus PRP. The second session was a combination of allogenic exosomes plus PRP done at six months. The third session was a combination of Stromal Vascular Fraction (SVF) plus PRP done at 10 months.”

The Right hip severity was assessed using the Harris Hip Score (HHS) and Western Ontario and McMaster Universities Osteoarthritis  Index  (WOMAC)  scale.  Radiologic  studies (X-ray and MRI) were done.

The results showed a positive outcome according to all the grading systems used in the study and the patient was followed up for 24 months and is still being followed up which is proving its advantage in long-term outcomes.

The research concluded that adult stem cell therapy is a promising alternative method of treatment in people with severe hip osteoarthritis.

Dr David Ikudaiyisi, said regenerative medicine involving adult stem cells is continually being studied and researched to gather more evidence to enable harnessing its’ clinical potential.

The use of adult stem cells for clinical therapy is now a reality for many patients who were not able to shed the yoke of many diseases that conventional medicine provided very little hope of permanent relief for.

He said, “Currently, adult stem cell therapy is now seen as a viable therapeutic alternative for joint and back pain, sexual dysfunction, diabetes, End Stage Renal Disease on hemodialysis, arthritis, etc.

“The treatments are gaining popularity among patients and doctors because it is natural and can help repair and regenerate most parts of the human tissues.”